Will partitioning slow down games?

I want to split my C drive up into C and D partitions. I am planning on putting all my games (very new one's) and personal data on D: and C: for system OS and applications. How much data for games on my D partition slow them down? is it a notice able slowdown? or will it only slow down loading times and not actual game performance? it is a 500gb HDD 5400rpm I am planning to do 80 or 100 for C: (curently using only up 25 GB) (should i just make it 50 for partition c?) and the rest for D:

Before installing any Game check for the requirements of that Game because the requirements of that game only monitors. As your C drive is have 100 gb you can make it partition. You must know the how much space occupies by that game this information is available in system requirements of that game and better dont install the game in C drive because if that game occupies 30 GB of data that might slow down your system and performance aswell.

Make sure that system requirements of that particular game meets your system configuration. Recommended partition for the C drive or primary partition is 50 GB. Minimum of 50 GB is required for the C drive to install an OS.